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KMID : 1101720210250020008
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Physical Activity and Nutrition
2021 Volume.25 No. 2 p.8 ~ p.14
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Consumption of a high-fat-high-sucrose diet partly diminishes mechanical and structural adaptations of cardiac muscle following resistance training
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Boldt Kevin
Mattiello Stela
Joumaa Venus
Turnbull Jeannine
Fedak Paul W. M.
Herzog Walter
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Abstract
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Purpose: The purpose of this study was to investigate the effects of a high-fat high-sucrose (HFHS) diet on previously reported adaptations of cardiac morphological and contractile properties to resistance training.
Methods: Twelve-week-old rats participated in 12-weeks of resistance exercise training and consumed an HFHS diet. Echocardiography and skinned cardiac muscle fiber bundle testing were performed to determine the structural and mechanical adaptations.
Results: Compared to chow-fed sedentary animals, both HFHS- and chow-fed resistance-trained animals had thicker left ventricular walls. Isolated trabecular fiber bundles from chow-fed resistance-trained animals had greater force output, shortening velocities, and calcium sensitivities than those of chow-fed sedentary controls. However, trabeculae from the HFHS resistance-trained animals had greater force output but no change in unloaded shortening velocity or calcium sensitivity than those of the chow-fed sedentary group animals.
Conclusion: Resistance exercise training led to positive structural and mechanical adaptations of the heart, which were partly offset by the HFHS diet.
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KEYWORD
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obesity, high-fat high-sucrose diet, cardiac adaptations, resistance exercise, skinned fibers, echocardiography
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